From Precision to Predictive: Genetic Revolution to Healthcare and Beyond
The transition from today’s system of generalized medicine based on population averages to the new model of precision healthcare based on each person’s individual biology is already well underway. But the use of the precision medicine tools of genome sequencing, big data analytics, and targeted gene therapies to treat cancer and other diseases are paving the way for a system of predictive healthcare where parents will know and begin responding to their children’s future risk of developing hereditary disorders like early onset Alzheimer’s and coronary heart disease starting before their children have even been born.
In addition to predicting these types of health outcomes, genetic analysis will also enable us to predict and ultimately influence the genetic components of broader human traits like the IQ, athletic ability, and personality style of our future children. The genetics revolution will fundamentally transform our healthcare, the way we make babies, and the nature of the babies we make, but health professionals, the business community, and society at large are not at all ready. In this provocative and mind-expanding talk, Jamie Metzl elucidates how genetic and other technologies are transforming healthcare, explores where things are headed and what is at stake, and lays out key principles for how health industry professionals and the business community can prepare for a revolution that is coming far sooner than most people recognize.
Is Your Business Ready for Exponential Change?
If the pace of technological change feels like it’s getting faster, that’s because it is. The basic idea of exponential change is that innovation begets innovation. The more and better tools we develop, the more efficiently and effectively we organize ourselves, and connect with each other; and the more ideas we have, the better positioned we are to devise even better tools, organize and connect more, and come up with ideas we could never have been imagined at the start. This is why it took around twelve thousand years to go from the agrarian revolution to the industrial revolution but only a couple of hundred years to move from the industrial revolution to the internet revolution and then only a few decades to arrive at the dawn of the AI revolution. Each technological revolution enables the next and the time between each revolution becomes shorter and the impact bigger. And because change is speeding up, our sense of timing based on past experience is by definition too conservative, or obsolete.
Exponential technological change may seem like an abstract concept but it will be disrupting your business far sooner than you think. Most everyone knows that automation will increasingly make many human work functions – from sales clerks to truck drivers to radiologists – obsolete, but few understand how the very model of corporate innovation is soon about to change or how the coming shift to a world of personalized health care with turn corporate human resource management on its head. In this wide-ranging, exhilarating, and deeply challenging talk, technology futurist, sci-fi novelist, and corporate guru Jamie Metzl helps business leaders understand how they can best ride the coming tidal wave of radical technological change toward a better and more competitive future.
What China’s CRISPR babies mean for you, your family, and the future of your business
Recent reports that a Chinese scientist engineered the genomes of a pair of twins are a harbinger of a scientific revolution that will quickly and fundamentally transform our healthcare, procreation, and individual and collective identities. Just like the first word out of a baby’s mouth is both a small step and an essential indication of something far more profound, the one change made in the Chinese embryos propels us into a world where we humans will be able to recast all life on earth, including our own. While this may feel like science fiction, the near-term impacts our on personal and professional lives are coming far sooner than most of us understand or are prepared for. In just a short number of years, companies will be need to figure out, for example, if and how to use genetic data when assessing the suitability of applicants and employees for given tasks, whether advanced egg freezing and embryo selection should be provided as corporate health benefits, and what to do when all employees’ sequenced genomes indicate multiple pre-existing conditions. The genetics revolution is coming far faster than you think -- but are you ready?
Jamie Metzl is among the world’s leading experts on the big picture implications of the genetics revolution. His latest book, Hacking Darwin: Genetic Engineering and the Future of Humanity, will be released in April 2019 and is already being widely acclaimed. “If you can read one book on the future of our species,” CNN’s Sanjay Gupta says, “this is it.”
R/Evolution at the Intersection of AI and Genomics
After decades of slow progress during the long “AI Winter,” the field of artificial intelligence is now blossoming in an “AI Spring” fundamentally transforming the way we live, work, and innovate. But the AI revolution won’t just change what we do, it will ultimately transform who we are. Most people already appreciate that genome sequencing and other genetic technologies will alter the way we treat cancer and other diseases. But the healthcare applications of genomics are just a station along the way in this profound revolution at the intersection of AI and Genomics. The ultimate destination is nothing less than the transformation of our evolutionary trajectory as a species. While the idea of creating humans with exceptional traits like higher IQ, disease resistance, or the ability to live longer and healthier lives may seem the stuff of science fiction, this future is far closer than most people understand or appreciate. In this mind-blowing and highly entertaining talk, futurist Jamie Metzl explains in clear, colorful, and concise language the coming revolution at the intersection of AI and genomics with its incredible promise and frightening danger, and explores what every person, company, and country can and must do to prepare.
How Thinking Like a Sci-Fi Writer Can Help Your Organization Ride the Wave of Revolutionary Change and Unlock your Hidden Potential
The future is coming at us faster than ever before. As the pace of technological change in fields like artificial intelligence, genomics, and robotics increases exponentially, the sands of national and international politics are shifting under our feet more than at any time since the end of WWII. But while this moment of radical change creates great peril for organizations that stick too rigidly to traditional ways of thinking and operating, it provides unparalleled opportunities for those who challenge themselves to think differently, creatively imagine future scenarios, and set out on a journey to succeed in a radically new environment. Organizations must, in other words, begin thinking like science fiction writers. In this wide-ranging and highly focused talk, sci-fi novelist, technology futurist, and geopolitical expert Jamie Metzl clearly explains the converging mega-trends reshaping our world, describes how science fiction writers draw on evidence from the present to build a world of tomorrow, and outlines a specific road map for how organizations can use the powerful tool of thinking more like science fiction writers to better prepare for the future and unlock hidden organizational potential.
What You Need to Know About the Future
Converging political, geopolitical, and technological revolutions are making now the greatest moment of global change at least since 1945 and possibly ever. With nationalism rising around the world, the post-war international order in rapid decline, China significantly expanding its global influence, and the AI, genetics, fintech, and other revolutions shaking the foundations of the world we’ve known, the pressure is mounting for individuals, companies, and countries to either understand and quickly adapt to these converging super-trends or pay a massive competitive price. In this talk spanning the wide range of factors transforming our world at lightning speed, geopolitical expert and technology futurist Jamie Metzl paints a vivid picture of where we are heading and outlines key principles for how individuals, companies, and countries can best position themselves to ride the rising tidal wave of revolutionary change.
Global Geopolitics in an Age of Trump
The "America First" foreign policy of the Trump administration is hastening the demise of the post-War international system that was already in a state of crisis. But how will global peace, security, and stability be maintained in a world that has become dependent on American internationalism? In this talk spanning five hundred years of history, Jamie Metzl explores how our world today is structured in response to the destruction of the two World Wars and what it will mean to return to a world defined by strong states in a balance of power system. As the post-War era draws to a close, the ghosts of history are returning with a vengeance -- with the world order, the global economic system, and the military balance hanging in the balance. The coming world disorder will create enormous challenges for companies and other organizations but even greater opportunities those who understand and prepare for what is coming.
Rising China and the Shifting Geopolitics of Asia
Fast-rising China is not just changing Asia, it is fundamentally transforming the global order. China’s economic growth, military expansion, behavior in the South and East China Seas, growing presence around the world, and increasingly emboldened foreign policy present a growing challenge to the US-led global system created in the aftermath of the Second World War. With America less able to serve as guarantor of the international system, and Europe incapable of realizing a coordinated foreign policy strategy and unwilling to invest sufficiently in military readiness, efforts to address major crises, promote a single set of rules governing the global economy, and support human rights around the world are faltering. But with China's investment and manufacturing-based growth strategy losing steam, China itself will need to find a new model if it is to avoid stagnation. Living in a post-American world will have enormous consequences and touch every aspect of our lives. In this exciting talk, Metzl gives explores the key drivers of our fundamentally transforming world, what it will mean for global politics, economics, and culture, and how businesses and other organizations can best prepare.
Can China Avoid Economic Crisis?
With China's investment and manufacturing-based growth strategy losing steam, the country will need to find a new model if it is to avoid stagnation or even economic crisis. China's leaders have excellent plans for this transition, but major questions remain about whether they can realize these plans under the constraints of their current political system. Asia and foreign relations expert Jamie Metzl discusses the bubbles, bottlenecks and problems facing the Chinese economy, China's impact on American and global trade, and the world implications of a sputtering Chinese economy.
What You Need to Know About Asia in One Hour and One Slide
Asia’s rapid rise is reversing a current of westernized globalization that has flown for five hundred years. Understanding how Asia is transforming itself and the world is no longer just a matter of curiosity for outsiders, it is essential to making smart decisions. In this wide-ranging talk spanning thousands of years and multiple cultures, Asia expert Metzl draws on history, culture, science, technology, and politics to explain the background, drivers, and implications of Asia’s rise.
Homo Sapiens 2.0: Genetic Enhancement, Life Extension, and How to Prepare for the Future of Humanity
After four billion years of evolution through the Darwinian principles of random mutation and natural selection, our species is about to take control of our evolution. The genetic revolution will allow us to eliminate genetic diseases which have plagued our ancestors for millennia, live longer healthier lives, and transform how we make babies and ultimately the nature of the babies we make. The genetics revolution will be the greatest opportunity of our era, and also the greatest challenge. A rare combination of technology expert and science fiction writer, Jamie brings the science to life and explains what people and companies can and should be doing now to prepare for this revolutionary future that will fundamentally reorganize modern societies and have monumental business implications.
Hacking Darwin: Genetic Engineering and the Future of Humanity
After four billion years of evolution through the Darwinian principles of random mutation and natural selection, our species is about to take control of our evolution. The genetic revolution will allow us to eliminate genetic diseases which have plagued our ancestors for millennia, live longer healthier lives, and transform how we make babies and ultimately the nature of the babies we make. The genetics revolution will be the greatest opportunity of our era, and also the greatest challenge – and it will have massive business implications that will increasingly define organizational success and failure in the 21st century.
Hacking immortality: The science and science fiction of extreme human life extension
In this exciting talk, Jamie Metzl explores the latest technological breakthroughs in the science of human life extension and their implications on the personal and societal levels. While the quest for immortality has been the stuff of fairy tales, the new science of life extension is very real and will soon be pushing the limits of aging and unlocking human potential. Jamie, a rare combination of science expert and science fiction writer, brings the science to life and explains what people can and should be doing now to prepare for this revolutionary future that will fundamentally reorganize modern societies and have monumental implications for businesses and other organizations.
Human Resource Management in a Genetic Age
Corporations have struggled for decades to build open and inclusive workplaces comfortable to people of all races, nationalities, genders, ages, and sexual orientations. In the fast-arriving genetic age, companies will need to figure out such issues as whether to cover embryo selection and embryonic genetic engineering for employees and how to deal with genetic IQ estimates derived before birth from the sequenced genomes of potential employees. While this may seem like science fiction, the beginnings of this future are already here. Today’s debate about whether or not companies should cover egg freezing expenses for female employees is only a first step in a genome-based transformation that will alter our perception of workforce capabilities and potentials and challenge even the most forward-thinking of corporations.
Are We on the Verge of a Genetic Arms Race?
The revolution in human genetic engineering that will make it possible for us to manage our evolutionary process for the first time in our species’ history is already underway. In laboratories and clinics around the world, gene therapies are being successfully tested to treat a range of diseases including immune deficiency, hemophilia and cancer; fetuses are being genetically screened to optimize the in vitro fertilization process. This miraculous progress is only a first step. Although we will soon eliminate many diseases which have victimized humans for hundreds of thousands of years, the same already existing technologies can and will be used to alter our genes and design our babies to make them smarter, stronger, and more robust.
The prospect of genetic engineering will be exciting to some, frightening to others, and challenging for all. It will also raise critical issues likely to lead to major conflict both within societies and globally if not adequately addressed. But while the science of human genetic engineering is charging forward at an exponential rate, the global policy framework to ensure this scientific progress does not lead to global conflict barely exists at all. In this talk, Metzl explores the global national security implications of the human genetics revolution and what can be done to try to avoid dangerous conflict.
Jamie Metzl in the news
Having served in high level positions in the White House, State Department, and Senate, as well as run a major international affairs organization, JAMIE METZL draws from his cutting edge experience in both the public and private sector to provide transformative insights and actionable takeaways for every audience. Here is a sampling of his media appearances:
12.11.2018 Inside the US-China rivalry | CNN Amanpour
Jamie Metzl, ahead of the genetics revolution
If the recent news of the Chinese genetically engineered babies was a surprise to you, it wasn’t for JAMIE METZL.
The technology futurist, geopolitical expert, and Atlantic Council Senior Fellow testified before the US congress over a decade ago predicting that humans would soon start genetically altering our future children. Since then, has been leading the call to governments and in forums around the world, the international media, and the pages of major journals for a thoughtful response.
Dubbed a “true polymath… bordering on the superhuman” and recognized for his advanced expertise in “AI, Genetics, and the Future” in the industry leading Psychology Today, Metzl states that we are “at the cusp of a genetic revolution that will transform our healthcare in the short term, how we make babies and the nature of the babies we make in the medium term, and our evolutionary trajectory as a species over the longer term.”
Metzl’s recent editorial in LeapsMag, a journal covering groundbreaking advances in life sciences, entitled Is Sex for Reproduction About to Become Extinct? makes the striking case for why ever-more humans will soon begin conceiving their children in labs and what this means for all of us.
The culmination of Metzl’s two decade-long deep dive into the science, politics, and ethics of the genetics revolution is the announcement of the April 23, 2019 publication of his fifth book, Hacking Darwin: Genetic Engineering and the Future of Humanity. Having garnered major attention at the recent Frankfurt Book Fair, the book has also received glowing reviews from preeminent geneticists and thought leaders:
“Metzl guides us brilliantly down the twisting and ever-changing river of our genetic future in this important and thought-provoking book… [and] thoughtfully explores the ultimately more critical issues of diversity, equality, and respect for each other and our common humanity.”
— George Church, Professor of Genetics at Harvard Medical School and author of Regenesis
“Metzl’s Hacking Darwin is an outstanding guide to the most important conversation of our lives — how we humans will hijack our evolutionary process and transcend the limits of our own biology.”
— Ray Kurzweil, inventor and futurist, author of The Singularity is Near and How to Create a Mind
"Metzl's book - ranging through genetics, human destiny and the future -- is an incredible trove of information for scientists, futurists, technologists, entrepreneurs, and virtually every intrigued, interested reader. A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril. This is a must-read book."
— Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene: An Intimate History
"In many ways, Jamie Metzl has been preparing Hacking Darwin for the last 20 years and his diligence shines through. Jamie is a gifted writer and his explanation of genetics are crisp, accurate, and wonderfully engaging. If you can only read one book on the future of our species, this is it."
— Sanjay Gupta MD, bestseller author, neurosurgeon, and Emmy-award winning chief medical correspondent (CNN)
The very real prospects of designer babies and self-driven human evolution may pose a daunting path for us personally and for all humankind, but Jamie Metzl has long been our ready guide for this journey.
“What Metzl has achieved in the seemingly disparate domains of athleticism and intellectualism is quite astonishing,” the Psychology Today profile reads, “but also he is warm, likable, down-to-earth, and humorous.”
Metzl is also a compelling speaker who paints a vivid picture of a future arriving far faster than most of us understand, or are prepared for, and wants us to understand what we each and all must do in our personal and professional lives to get ready.
Jamie Metzl sought-out for sharp analysis on Asia
As the North Korea crisis unfolds by the day and the likelihood of a US-China trade war increases, Asia expert, former White House official, and regular CNN contributor JAMIE METZL is uniquely qualified to shed light on these crucial situations, providing sharp analysis on what individuals, businesses and organizations can expect. Having penned a powerful and informative editorial for CNN entitled “12 things Trump should know about North Korea,” delivered a keynote at China’s most important gathering on North Korea, and spoken at HSBC’s China Forums in both New York and San Francisco, Metzl is highly in-demand for his shrewd insights on the impacts of what’s happening in Asia. What would a fully nuclear armed North Korea mean for the United States, Asia, and the world? What should the world expect from China’s critical party congress at the end of this year? Drawing on his extensive experience advising both the North and South Korean governments, serving as director on the U.S. National Security Council, and recently engaging in extensive consultation with experts on the China-North Korea border, Metzl is able to answer all of these questions and more. In his inside view, tour de force talks, he explains the North Korea crisis, the often conflicting interests of Asia’s key players, the options going forward, and the implications of all of this for the region and world.Watch Metzl speak on CNN >>
Jamie Metzl on the Trump administration's foreign policy and ethical lapses
The news media plays an absolutely essential role in our democracy and society and it is simply not acceptable for any US president to call the media the "enemy of the people." Events like the Trump-inspired chanting of "CNN sucks" inspired JAMIE METZL to share with you, proudly, his CNN interviews on the administration's dangerous foreign policy and ethical lapses.
Homo Sapiens 2.0? Jamie Metzl, Senior Fellow for Technology and National Security at the Atlantic Council, calls for a species-wide conversation about the future of human genetic enhancement.
With the science of genetic human enhancement moving forward exponentially, we will have big social problems if an inclusive public conversation does not accompany this miraculous technological advancement.
Jamie Metzl is a leading futurist who specializes in making revolutionary science understandable to the general public. He speaks regularly at some of the world’s most prestigious venues including South by Southwest, Google Zeitgeist, and Singularity University, and is a regular guest on CNN, Bloomberg, BBC, CBS, and other national and international media. His syndicated columns and other writing on genetics, virtual reality, Asian affairs, and other topics are featured regularly in the New York Times, Washington Post, TechCrunch, Foreign Affairs, and other publications around the world. Jamie is the author of a history of the Cambodian genocide, the historical novel The Depths of the Sea, and the genetics sci-fi thrillers Genesis Code and Eternal Sonata. His non-fiction work Homo Sapiens 2.0: Genetic Enhancement and the Future of Humanity will be released by Source Books in Spring 2019.
Jamie is an founding member of the WHO Expert Advisory Committee on Developing Global Standards for Governance and Oversight of Human Genome Editing, a Senior Fellow for Technology and National Security of the Atlantic Council, a faculty member for Singularity University’s Exponential Medicine track, and an expert in international affairs and biotechnology policy. He previously served as Executive Vice President of the Asia Society, Deputy Staff Director of the U.S. Senate Foreign Relations Committee, Senior Coordinator for International Public Information at the U.S. State Department, Director for Multilateral Affairs on the National Security Council, and as a Human Rights Officer for the United Nations in Cambodia. He has testified before Congress on the national security implication of the biotechnology and genomics revolutions and was Chief Strategy Officer for a genetics biotechnology company.
A founder and Co-Chair of the national security organization Partnership for a Secure America, Jamie is a board member of the International Center for Transitional Justice and the American University in Mongolia, a member of the Advisory Board of the Brandeis International Center for Ethics, Justice, and Public Life and 92Y’s Center for Innovation and Social Impact. A member of the Council on Foreign Relations and former White House Fellow and Aspen Institute Crown Fellow, Jamie holds a Ph.D. in Asian history from Oxford, a JD from Harvard Law School, and is a magna cum laude, Phi Beta Kappa graduate of Brown University. He has completed thirteen Ironman triathlons, twenty-nine marathons, and twelve ultramarathons.
For more on Jamie, including links to many of his media appearances, talks, books, and articles, please see www.jamiemetzl.com.