During his tenure as NASA’s longest-serving Administrator, The Honorable Dan S. Goldin transformed America’s aeronautics and space program. He is credited with the re-emergence of NASA after the Cold War. Despite lower budgets, his “faster, better, cheaper” approach enabled the Agency to deliver programs of high value to the American public without sacrificing safety. Prior to his tenure at NASA, Mr. Goldin served as a leading national security executive, producing systems of high national priority. As the founder of Cold Canyon, an innovation advisory company, and as a senior advisor to Cerberus Capital Management, his career spans space exploration and science, aeronautics, air traffic management, national security systems, semiconductors, advanced sensors, hypersonic, communications, and artificial intelligence. With his accumulated experience, Mr. Goldin is a highly sought-after leader in advancing American technologies and businesses. Mr. Goldin has recently spoken at SXSW, the Space Symposium, Purdue University, the International Aviation Women’s Association, and many more.

Mr. Goldin is a Member of the National Academy of Engineering, and the Krach Institute for Tech Diplomacy. He is a Fellow of the American Institute for Aeronautics and Astronautics and the American Astronautical Society, and an Honorary Board Member of the Explorers Club.  Mr. Goldin has received the Goddard Memorial Trophy, the premier award from the National Space Club and Foundation, and the General James E. Hill Lifetime Space Achievement Award, the highest honor bestowed by the Space Foundation. Mr. Goldin holds 18 Honorary Doctorates from the world’s great universities. As a deep tech champion, Mr. Goldin brings firsthand expertise to the stage, empowering audiences to navigate and harness cutting-edge technologies for transformative business growth and innovation. 

MIT-trained engineer and tech entrepreneur Krisztina “Z” Holly, curator of the first ever TEDx event, has been at the forefront of innovation throughout her career. She started her career as a serial tech entrepreneur in Boston and Silicon Valley before spending over a decade building pioneering innovation centers at MIT and USC. The White House subsequently invited her to help spread her novel model across the United States. Today, she invests in early-stage complex science and technology startups as an operating partner at Good Growth Capital and is a sought-after advisor and speaker to organizations around the world. She has been recognized by Rolling Stone, Forbes, WIRED, and Entrepreneur Mag for her ability to scout and cultivate talent and catalyze global initiatives. With a proven track record of fostering innovation, Z’s insights come from real-world experience.

Z has spoken at Davos, the White House, YPO Entrepreneurial Energy, NBC Universal, and the National Academy of Sciences Innovation Summit; she has facilitated numerous sessions for the World Economic Forum with heads of state and CEOs of Fortune 100 companies. She regularly appears as a public expert and interviewer, leading conversations with tech “rockstars” such as Biz Stone and Tim O'Reilly, interviewing world-famous extreme athletes, and facilitating panels with university presidents and global leaders. Z’s authentic style and tailored messages resonate with a wide range of audiences, from students and aspiring entrepreneurs to academics and top executives. 

A Visionary Leader in Healthcare Innovation and Healthcare Policy

Dr. Francis Collins is one of the most influential scientists and healthcare policy leaders of our time, recognized for his groundbreaking contributions to genomics, precision medicine, and national healthcare initiatives. As the Director of the National Institutes of Health (NIH) from 2009 to 2021, he played a pivotal role in shaping the nation’s biomedical research agenda under three U.S. Presidents—Barack Obama, Donald Trump, and Joe Biden. His leadership was instrumental in advancing critical research on diabetes, Alzheimer’s disease, cancer, neuroscience, genetic diseases, and the COVID-19 pandemic.

Revolutionizing Medicine: The Human Genome Project and Beyond

Before his tenure as Director of NIH, Dr. Collins led one of the most significant scientific efforts in modern history—the Human Genome Project. Completed in 2003, this international collaboration successfully mapped the entire human genetic code, revolutionizing genetic medicine, diagnostics, and targeted therapies. His leadership in genomics has had a lasting impact on precision medicine, transforming the way diseases are prevented, diagnosed, and treated.

Physician and geneticist Dr. Francis Collins' life story is one of curiosity, discovery, and deep human connection. His journey from a small-town upbringing to leading the Human Genome Project and serving as Director of the National Institutes of Health is a testament to the power of vision, intellectual courage, and ethical leadership.

Guiding National Healthcare Policy and Research

As NIH Director, Collins secured bipartisan support for major healthcare initiatives, fostering public-private partnerships to accelerate biomedical innovation. Under his leadership:

• The Cancer Moonshot Initiative was launched to advance cancer research and treatment.
• The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative pushed the frontiers of neuroscience.
• The All of Us Research Program paved the way for precision medicine by collecting diverse genetic and health data on close to a million Americans, to drive personalized treatment strategies.
• NIH-led COVID-19 vaccine and treatment research played a crucial role in the rapid development of mRNA vaccines and therapeutics.
• Global health research was a major priority for NIH, including launching the H3Africa Project and assisting in the design of an African Centers of Excellence Program.
• The Sound Health Program, co-led with Renée Fleming, brought together music therapists, neuroscientists, and performers to identify new ways for music to be used for healing.

A Lifelong Commitment to Science and Innovation

Following his tenure as Acting Science Advisor and Special Projects Advisor to President Biden (2022-2023), Collins returned to his NIH research laboratory to continue investigating genetic factors in diabetes and premature aging. He retired from NIH on March 1, 2025, but continues to be a leading voice advocating for the importance of support of biomedical research. 

Elizabeth Sherwood-Randall has tackled the world’s most pressing global and domestic challenges for four decades. Leading in top public roles, including as White House Homeland Security Advisor and Deputy National Security Advisor (2021-2025), Deputy Secretary of the United States Department of Energy (2014-2017), White House Coordinator for Defense Policy, Countering Weapons of Mass Destruction, and Arms Control (2013-2014), Special Assistant to the President and Senior Director for European Affairs (2009-2013), and at the Pentagon as Deputy Assistant Secretary of Defense for Russia, Ukraine and Eurasia (1994-1996), Sherwood-Randall has worked on the most complex and consequential global challenges, participating in the highest levels of international and domestic decision-making. Sherwood-Randall’s expertise spans a broad range of topics that are highly relevant today, including leading through crises, securing critical infrastructure, driving energy innovation, and conducting international diplomacy with both allies and adversaries.

Offering unique insights and unparalleled expertise across a spectrum of issues, from homeland security to national security, Sherwood-Randall presents the threats and opportunities that lie ahead through a compelling insider’s lens. Her work in both the top levels of the American government and with private sector partners highlights her ability to bring innovative solutions to complex challenges. She offers insights on reducing threats, navigating uncertainty, managing emergencies, and making tough decisions under pressure in the media spotlight. With first-hand experience as a defense and energy policy leader, global crisis manager, and proven female executive, Sherwood-Randall has inspired numerous teams to achieve ambitious goals, facing dynamic times with courage, steadiness, and grace under pressure.

Harvard University professor of philosophy Michael Sandel has been described as a “philosopher with the global profile of a rock star,” known across the globe for his lively Socratic debates that aim to restore the lost art of respectful discussion. Sandel is the bestselling author of books on justice, ethics, democracy, and markets that have been translated into over 30 languages. Sandel has been a visiting professor at the Sorbonne, delivered the Tanner Lectures on Human Values at Oxford, served on the U.S. President’s Council on Bioethics, and is a member of the American Academy of Arts and Sciences. A graduate of Brandeis University, he received his doctorate from Oxford University, where he was a Rhodes Scholar.

Sandel’s books—on justice, democracy, ethics, technology, and markets—have been translated into more than 30 languages. They include Justice: What’s the Right Thing to Do?; What Money Can’t Buy, and The Tyranny of Merit: Can We Find the Common Good?, which seeks a way beyond our polarized politics. A new edition of his classic book Democracy’s Discontent has been described as “essential--and ultimately hopeful--reading for all those who wonder if our democratic experiment will survive in the twenty-first century.”

Sandel’s legendary course “Justice,” one of the most popular in Harvard’s history, is freely available online and has been viewed by tens of millions. His BBC series The Global Philosopher engages participants from around the world in discussing the ethical issues lying behind the headlines. In this and other television, radio, and online programs, Sandel explores tech ethics, robots and AI, markets and morals, climate change, free speech, and other topical issues.

Sandel’s renowned interactive public lectures on the big civic questions of the day show how reasoned debate, leavened with humor and mutual respect, can produce dialogue across our differences.

A “master of life’s big questions” (Guardian), Sandel’s live events have packed St. Paul’s Cathedral (London), the Sydney Opera House (Australia), the Delacorte Theater in New York’s Central Park, and an outdoor stadium in Seoul (S. Korea), where 14,000 came to hear him speak.